Liste des projets de l'équipe
Liste des anciens membres de l'équipe
Pedro F. Vale
Centre d’Ecologie Fonctionnelle et Evolutive
CEFE-UMR 5175
1919 route de Mende
34293 Montpellier
France
email: Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser.
tel: +33 4 67 61 32 96
Research
I am broadly interested in the evolutionary ecology of host-pathogen interactions.
My research uses experimental infections in host-parasite model systems to investigate questions about the epidemiology, ecology, and evolution of infectious disease. A common theme in my work has been context-dependent infection: in order to understand how disease will spread and evolve, it is necessary to study infection in the lab under the variable genetic and environmental contexts that hosts and parasites will commonly experience in the wild. My current interests focus on how variation in resistance and tolerance to infection at the level of individual hosts may influence the epidemiology and evolution of disease at the population level.
2010 – Present| Postdoctoral researcher
Advisor: Sylvain Gandon
CEFE CNRS – Montpellier, France
2005-2009| PhD in Evolutionary Biology
Thesis: “Infection outcomes under genetic and environmental variation: implications for the maintenance of polymorphism and the evolution of virulence”
Advisor: Tom Little
Institute of Evolutionary Biology, University of Edinburgh, UK
2004-2005| GABBA Graduate Program in Areas of Basic and Applied Biology
Advisor: Maria de Sousa
University of Porto, Portugal
1999-2004| Degree (BSc+MSc) in Biology
University of Evora, Portugal
Publications
Vale PF, Choisy M, Little TJ. Identifying risk factors for disease super-spreading using experimental infections.
Garbutt JS, Scholefield JA, Vale PF, Little TJ. Elevated maternal temperature enhances offspring disease resistance in Daphnia magna.
Vale PF, Little TJ. Fecundity compensation and tolerance to a sterilizing pathogen in Daphnia. Journal of Evolutionary Biology. DOI: 10.1111/j.1420-9101.2012.02579.x [abstract in JEB]
Vale PF, Choisy M, Froissart R, Sanjuan R, Gandon S. (2012) The distribution of mutational fitness effects of phage &phiX174 on different hosts. Evolution. DOI: 10.1111/j.1558-5646.2012.01691.x [Abstract at Evolution]
Fellous S, Duncan A, Quillery E, Vale PF & Kaltz O. (2012) Genetic influence on disease spread following arrival of infected carriers.Ecology Letters. 15:186–192. [Abstract at Ecology Letters].
Vale PF, Wilson AJ, Best A, Boots M, Little TJ. (2011) Epidemiological, evolutionary, and coevolutionary implications of context-dependent parasitism. The American Naturalist 177:510-521. [Abstract at Am Nat] [Supplementary material] [Press release].
Labbé P, Vale PF, Little TJ. (2010) Successfully resisting a pathogen is rarely costly in Daphnia magna. BMC Evolutionary Biology 10:355. [BioMed Central].
Vale PF, Little TJ. (2010) CRISPR-mediated phage resistance and the ghost of co-evolution past. Proceedings of the Royal Society of London – Biological Sciences 277:2097-2103. [EXiS Open Choice].
Vale PF (2009) Infection outcomes under genetic and environmental variation: implications for the maintenance of polymorphism and the evolution of virulence. PhD thesis. Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK [Edinburgh Research Archive].
Vale PF, Little TJ. (2009) Measuring parasite fitness under genetic and thermal variation. Heredity103: 102–109. [Abstract at Heredity].
Vale PF, Stjernman M, Little TJ. (2008 ) Temperature dependent costs of parasitism and maintenance of polymorphism under genotype-by-environment interactions. Journal of Evolutionary Biology 21: 1418-1427 [Abstract at JEB].
Vale PF, Salvaudon L, Kaltz O, Fellous S (2008) The role of the environment in the evolutionary ecology of host-parasite interactions. Infection, Genetics and Evolution 8(3):302-305 [Abstract at IGE].
Little TJ, Birch J, Vale P and Tseng, M (2007) Parasite transgenerational effects on infection. Evolutionary Ecology Research 9(3):459-469.
Vale PF (2004) [Comportamento social em bactérias: o papel dos cheaters na evolução da resistência a antibióticos] Bacterial social behaviour: the role of cheaters in the evolution of antibiotic resistance. Thesis. [UEBIB TFC 03-063] Universdade de Évora, Portugal.
Pedro F. Vale
Centre d’Ecologie Fonctionnelle et Evolutive
CEFE-UMR 5175
1919 route de Mende
34293 Montpellier
France
email:Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser.
tel: +33 4 67 61 32 96
Research
I am broadly interested in the evolutionary ecology of host-pathogen interactions.
My research uses experimental infections in host-parasite model systems to investigate questions about the epidemiology, ecology, and evolution of infectious disease. A common theme in my work has been context-dependent infection: in order to understand how disease will spread and evolve, it is necessary to study infection in the lab under the variable genetic and environmental contexts that hosts and parasites will commonly experience in the wild. My current interests focus on how variation in resistance and tolerance to infection at the level of individual hosts may influence the epidemiology and evolution of disease at the population level.
2010 – Present| Postdoctoral researcher
Advisor: Sylvain Gandon
CEFE CNRS – Montpellier, France
2005-2009| PhD in Evolutionary Biology
Thesis: “Infection outcomes under genetic and environmental variation: implications for the maintenance of polymorphism and the evolution of virulence”
Advisor: Tom Little
Institute of Evolutionary Biology, University of Edinburgh, UK
2004-2005| GABBA Graduate Program in Areas of Basic and Applied Biology
Advisor: Maria de Sousa
University of Porto, Portugal
1999-2004| Degree (BSc+MSc) in Biology
University of Evora, Portugal
Publications
Vale PF, Choisy M, Little TJ. Identifying risk factors for disease super-spreading using experimental infections.
Garbutt JS, Scholefield JA, Vale PF, Little TJ. Elevated maternal temperature enhances offspring disease resistance in Daphnia magna.
Vale PF, Little TJ. Fecundity compensation and tolerance to a sterilizing pathogen in Daphnia. Journal of Evolutionary Biology. DOI: 10.1111/j.1420-9101.2012.02579.x [abstract in JEB]
Vale PF, Choisy M, Froissart R, Sanjuan R, Gandon S. (2012) The distribution of mutational fitness effects of phage &phiX174 on different hosts. Evolution. DOI: 10.1111/j.1558-5646.2012.01691.x [Abstract at Evolution]
Fellous S, Duncan A, Quillery E, Vale PF & Kaltz O. (2012) Genetic influence on disease spread following arrival of infected carriers.Ecology Letters. 15:186–192. [Abstract at Ecology Letters].
Vale PF, Wilson AJ, Best A, Boots M, Little TJ. (2011) Epidemiological, evolutionary, and coevolutionary implications of context-dependent parasitism. The American Naturalist 177:510-521. [Abstract at Am Nat] [Supplementary material] [Press release].
Labbé P, Vale PF, Little TJ. (2010) Successfully resisting a pathogen is rarely costly in Daphnia magna. BMC Evolutionary Biology 10:355. [BioMed Central].
Vale PF, Little TJ. (2010) CRISPR-mediated phage resistance and the ghost of co-evolution past. Proceedings of the Royal Society of London – Biological Sciences 277:2097-2103. [EXiS Open Choice].
Vale PF (2009) Infection outcomes under genetic and environmental variation: implications for the maintenance of polymorphism and the evolution of virulence. PhD thesis. Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK [Edinburgh Research Archive].
Vale PF, Little TJ. (2009) Measuring parasite fitness under genetic and thermal variation. Heredity103: 102–109. [Abstract at Heredity].
Vale PF, Stjernman M, Little TJ. (2008 ) Temperature dependent costs of parasitism and maintenance of polymorphism under genotype-by-environment interactions. Journal of Evolutionary Biology 21: 1418-1427 [Abstract at JEB].
Vale PF, Salvaudon L, Kaltz O, Fellous S (2008) The role of the environment in the evolutionary ecology of host-parasite interactions. Infection, Genetics and Evolution 8(3):302-305 [Abstract at IGE].
Little TJ, Birch J, Vale P and Tseng, M (2007) Parasite transgenerational effects on infection. Evolutionary Ecology Research 9(3):459-469.
Vale PF (2004) [Comportamento social em bactérias: o papel dos cheaters na evolução da resistência a antibióticos] Bacterial social behaviour: the role of cheaters in the evolution of antibiotic resistance. Thesis. [UEBIB TFC 03-063] Universdade de Évora, Portugal.
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