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Pedro Vale

Postdoc

Pedro F. Vale
Centre d’Ecologie Fonctionnelle et Evolutive
CEFE-UMR 5175
1919 route de Mende
34293 Montpellier
France

email: Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser.

tel:            +33 4 67 61 32 96    

 

Research

 

I am broadly interested in the evolutionary ecology of host-pathogen interactions.

My research uses experimental infections in host-parasite model systems to investigate questions about the epidemiology, ecology, and evolution of infectious disease.  A common theme in my work has been context-dependent infection: in order to understand how disease will spread and evolve, it is necessary to study infection in the lab under the variable genetic and environmental contexts that hosts and parasites will commonly experience in the wild.  My current interests focus on how variation in resistance and tolerance to infection at the level of individual hosts may influence the epidemiology and evolution of disease at the population level.

Brief CV

 

2010 – Present| Postdoctoral researcher 
Advisor: Sylvain Gandon
CEFE CNRS – Montpellier, France

2005-2009| PhD in Evolutionary Biology
Thesis: “Infection outcomes under genetic and environmental variation: implications for the maintenance of polymorphism and the evolution of virulence”
Advisor: Tom Little
Institute of Evolutionary Biology, University of Edinburgh, UK

2004-2005| GABBA Graduate Program in Areas of Basic and Applied Biology
Advisor: Maria de Sousa
University of Porto, Portugal

1999-2004|  Degree (BSc+MSc) in Biology
University of Evora, Portugal

 

 

Publications

 

 

Submitted

Vale PF, Choisy M, Little TJ. Identifying risk factors for disease super-spreading using experimental infections. 

Garbutt JS, Scholefield JA, Vale PF, Little TJ. Elevated maternal temperature enhances offspring disease resistance in Daphnia magna.

2012

Vale PF, Little TJ. Fecundity compensation and tolerance to a sterilizing pathogen in Daphnia. Journal of Evolutionary Biology. DOI: 10.1111/j.1420-9101.2012.02579.x [abstract in JEB]

Vale PF, Choisy M, Froissart R, Sanjuan R, Gandon S. (2012)  The distribution of mutational fitness effects of phage &phiX174 on different hostsEvolution.  DOI: 10.1111/j.1558-5646.2012.01691.x [Abstract at EvolutionF1000 Article

Fellous S, Duncan A, Quillery E, Vale PF & Kaltz O. (2012) Genetic influence on disease spread following arrival of infected carriers.Ecology Letters. 15:186–192. [Abstract at Ecology Letters].

2011

Vale PF, Wilson AJ, Best A, Boots M, Little TJ. (2011) Epidemiological, evolutionary, and coevolutionary implications of context-dependent parasitismThe American Naturalist 177:510-521. [Abstract at Am Nat] [Supplementary material] [Press release].

2010

Labbé P, Vale PF, Little TJ. (2010) Successfully resisting a pathogen is rarely costly in Daphnia magnaBMC Evolutionary Biology 10:355. [BioMed Central].

Vale PF, Little TJ. (2010) CRISPR-mediated phage resistance and the ghost of co-evolution pastProceedings of the  Royal Society of London – Biological Sciences 277:2097-2103. [EXiS Open Choice].

2009

Vale PF (2009) Infection outcomes under genetic and environmental variation: implications for the maintenance of polymorphism and the evolution of virulencePhD thesis. Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK [Edinburgh Research Archive].

Vale PF, Little TJ. (2009) Measuring parasite fitness under genetic and thermal variationHeredity103: 102–109. [Abstract at Heredity].

2008

Vale PF, Stjernman M, Little TJ. (2008 ) Temperature dependent costs of parasitism and maintenance of polymorphism under genotype-by-environment interactionsJournal of Evolutionary Biology 21: 1418-1427 [Abstract at JEB].

Vale PF, Salvaudon L, Kaltz O, Fellous S (2008) The role of the environment in the evolutionary ecology of host-parasite interactionsInfection, Genetics and Evolution 8(3):302-305 [Abstract at IGE].

2007 and beyond

Little TJ, Birch J, Vale P and Tseng, M (2007) Parasite transgenerational effects on infectionEvolutionary Ecology Research 9(3):459-469.

Vale PF (2004) [Comportamento social em bactérias: o papel dos cheaters na evolução da resistência a antibióticos] Bacterial social behaviour: the role of cheaters in the evolution of antibiotic resistanceThesis. [UEBIB TFC 03-063] Universdade de Évora, Portugal.

Pedro Vale

Postdoc

Pedro F. Vale
Centre d’Ecologie Fonctionnelle et Evolutive
CEFE-UMR 5175
1919 route de Mende
34293 Montpellier
France

email:Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser.

tel:            +33 4 67 61 32 96   

Research

I am broadly interested in the evolutionary ecology of host-pathogen interactions.

My research uses experimental infections in host-parasite model systems to investigate questions about the epidemiology, ecology, and evolution of infectious disease.  A common theme in my work has been context-dependent infection: in order to understand how disease will spread and evolve, it is necessary to study infection in the lab under the variable genetic and environmental contexts that hosts and parasites will commonly experience in the wild.  My current interests focus on how variation in resistance and tolerance to infection at the level of individual hosts may influence the epidemiology and evolution of disease at the population level.

BriefCV

2010 – Present| Postdoctoral researcher 
Advisor: Sylvain Gandon
CEFE CNRS – Montpellier, France

2005-2009| PhD in Evolutionary Biology
Thesis: “Infection outcomes under genetic and environmental variation: implications for the maintenance of polymorphism and the evolution of virulence”
Advisor: Tom Little
Institute of Evolutionary Biology, University of Edinburgh, UK

2004-2005| GABBA Graduate Program in Areas of Basic and Applied Biology
Advisor: Maria de Sousa
University of Porto, Portugal

1999-2004|  Degree (BSc+MSc) in Biology
University of Evora, Portugal

Publications

 

Submitted

Vale PF, Choisy M, Little TJ. Identifying risk factors for disease super-spreading using experimental infections. 

Garbutt JS, Scholefield JA, Vale PF, Little TJ. Elevated maternal temperature enhances offspring disease resistance in Daphnia magna.

2012

Vale PF, Little TJ. Fecundity compensation and tolerance to a sterilizing pathogen in Daphnia. Journal of Evolutionary Biology. DOI: 10.1111/j.1420-9101.2012.02579.x [abstract in JEB]

Vale PF, Choisy M, Froissart R, Sanjuan R, Gandon S. (2012)  The distribution of mutational fitness effects of phage &phiX174 on different hostsEvolution.  DOI: 10.1111/j.1558-5646.2012.01691.x [Abstract at EvolutionF1000 Article

Fellous S, Duncan A, Quillery E, Vale PF & Kaltz O. (2012) Genetic influence on disease spread following arrival of infected carriers.Ecology Letters. 15:186–192. [Abstract at Ecology Letters].

2011

Vale PF, Wilson AJ, Best A, Boots M, Little TJ. (2011) Epidemiological, evolutionary, and coevolutionary implications of context-dependent parasitismThe American Naturalist 177:510-521. [Abstract at Am Nat] [Supplementary material] [Press release].

2010

Labbé P, Vale PF, Little TJ. (2010) Successfully resisting a pathogen is rarely costly in Daphnia magnaBMC Evolutionary Biology 10:355. [BioMed Central].

Vale PF, Little TJ. (2010) CRISPR-mediated phage resistance and the ghost of co-evolution pastProceedings of the  Royal Society of London – Biological Sciences 277:2097-2103. [EXiS Open Choice].

2009

Vale PF (2009) Infection outcomes under genetic and environmental variation: implications for the maintenance of polymorphism and the evolution of virulencePhD thesis. Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK [Edinburgh Research Archive].

Vale PF, Little TJ. (2009) Measuring parasite fitness under genetic and thermal variationHeredity103: 102–109. [Abstract at Heredity].

2008

Vale PF, Stjernman M, Little TJ. (2008 ) Temperature dependent costs of parasitism and maintenance of polymorphism under genotype-by-environment interactionsJournal of Evolutionary Biology 21: 1418-1427 [Abstract at JEB].

Vale PF, Salvaudon L, Kaltz O, Fellous S (2008) The role of the environment in the evolutionary ecology of host-parasite interactionsInfection, Genetics and Evolution 8(3):302-305 [Abstract at IGE].

2007 and beyond

Little TJ, Birch J, Vale P and Tseng, M (2007) Parasite transgenerational effects on infectionEvolutionary Ecology Research 9(3):459-469.

Vale PF (2004) [Comportamento social em bactérias: o papel dos cheaters na evolução da resistência a antibióticos] Bacterial social behaviour: the role of cheaters in the evolution of antibiotic resistanceThesis. [UEBIB TFC 03-063] Universdade de Évora, Portugal.

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