Ingénieur de recherche au CNRS - Docteur en Chimie des biomoléculesEcochimiothèque : Il s'agit d'une base de donnée à l'interface Ecologie/Chimie initié par le GDR MediatEC en 2010. Elle a pour objectif de réunir les données des deux disciplines, du prélèvement aux molécules identifiées dans l'échantillon. L'EcoChimiothèque a été fermée en 2018. Les utilisateurs sont encouragés à consulter MetaboLights géré par l'EMBL-EBI.
Petit guide de Chimie pour l'Ecologie chimique (1ère partie, nomenclature et stéréochimie - 2ème partie , voies métaboliques) : Nous rédigeons actuellement avec Olivier Thomas un petit guide des bases nécessaires en Chimie pour travailler en Ecologie chimique. Ce document fait suite à un premier travail réalisé par nos collègues du GDR MediatEC autour du traitement statistique des analyses chimiques.
MZMine : un tutoriel pour le traitement de données GC-MS simple Quad à l'aide de MZmine. Pour la version "custom" 2.18 utilisée précédemment, elle est disponible sur
Bibliographie
A Leconte, N Barthes, B Buatois, E Coutagne, H Duval, P Lucas and M Staudt. Volatile organic compound emissions from almond shoots during spring—dissociation between reproductive and vegetative organs. Comptes Rendus. Chimie 26:1-16, 2023. DOI BibTeX
@article{leconte_volatile_organic_compound_2023_hal-04193216, title = "Volatile organic compound emissions from almond shoots during spring—dissociation between reproductive and vegetative organs", volume = 26, issn = "1631-0748", doi = "10.5802/crchim.241", abstract = "Prunus dulcis, a fruit tree of global economic and nutritional importance, is infested by Eurytoma amygdali, the almond wasp, due to the lack of biocontrol measures. This study characterizes the volatile organic compounds (VOCs) emitted by almond trees. We identified and quantified by GC-MS 44 VOCs emitted during spring. VOCs emitted during flowering were benzaldehyde and 1,4-dimethoxybenzene, while VOCs emitted during fruit and leaf growth were mainly sesquiterpenes. Emissions increased with temperature but light did not affect short-term emissions. VOCs identified in this study could be used to develop a biocontrol method to prevent infestation", journal = "Comptes Rendus. Chimie", author = "Leconte, A. and Barthes, N. and Buatois, B. and Coutagne, E. and Duval, H. and Lucas, P. and Staudt, M.", pages = "1-16", year = 2023, hal_id = "hal-04193216", peer_reviewing = 1, audience = 2, hal_version = "v1" }C Vernier, N Barthes, M -P Chapuis, J Foucaud, J Huguenin, N Leménager and C Piou. Faeces’ odours attract gregarious locust hoppers. Journal of Insect Physiology 143:104454, 2022. URL, DOI BibTeX
@article{vernier_faeces’_odours_attract_2022_hal-03969210, title = "Faeces’ odours attract gregarious locust hoppers", volume = 143, issn = "0022-1910", url = "https://www.sciencedirect.com/science/article/abs/pii/S0022191022001007", doi = "10.1016/j.jinsphys.2022.104454", abstract = "Highlights: • We hypothesize that attraction to fresh faeces enhance locust hopper band cohesion. • We exposed third instar hoppers of desert locust to faeces odours of different ages. • We observed an attraction of faeces explained by 11 volatile organic compounds. • Latecomers could get back to the band following faeces’ odours after 24 h. Abstract: Collective motion is one of the most impressive common features of gregarious locusts: once formed, bands and swarms get moving for long distances. It was shown that visual perception of neighbours plays a key role in maintaining marching behaviour at a local scale. But at a larger scale, mechanisms underlying band cohesion are less understood. It was shown in several field studies that individuals separated from the band were able to get back to the group, even after being separated since a night. In this context, faeces’ odours could be a possible indicator of the recent passage of a group. In this study, we tested if nymphs are attracted by faeces’ odours and if this effect is modulated by the age of the faeces. To this end, we conducted individual olfactometric behavioural assays of instar hoppers of desert locust, Schistocerca gregaria, exposed to odours of 1 h-old and 24 h-old faeces. We also used Gas Chromatography-Mass Spectrometry (GC–MS) to identify odours’ volatile organic compounds from faeces. The results of behavioural assays indicated a strong attractive effect of faeces, with no preference for one of the two faecal age classes. Nymphs spent significantly more time in the side of the olfactometer where the faeces’ odours came from, and 72.7% of tested individuals chose this side first. We filtered and annotated 11 volatile organic compounds present in both fresh and old faeces in GC–MS analyses, including guaiacol and phenol, which are known to cause an aggregative effect on desert locusts. As the attractive effect lasted over 24 h, band’s faeces could still have an attractive effect when individuals are separated from the band since one day. In this situation, latecomers individuals would be able to get back to the group by following the traces of their predecessors.", journal = "Journal of Insect Physiology", author = "Vernier, C. and Barthes, N. and Chapuis, M.-P. and Foucaud, J. and Huguenin, J. and Leménager, N. and Piou, C.", pages = 104454, pmid = 36343666, year = 2022, hal_id = "hal-03969210", peer_reviewing = 1, audience = 2, hal_version = "v1" }F Mondet, S Blanchard, N Barthes, D Beslay, C Bordier, G Costagliola, M R Hervé, B Lapeyre, S H Kim, B Basso, A R Mercer and Y L Conte. Chemical detection triggers honey bee defense against a destructive parasitic threat. Nature Chemical Biology 17:524+, 2021. DOI BibTeX
@article{mondet_chemical_detection_triggers_2021_hal-03121517, title = "Chemical detection triggers honey bee defense against a destructive parasitic threat", volume = 17, issn = "1552-4450", doi = "10.1038/s41589-020-00720-3", abstract = "Invasive species events related to globalization are increasing, resulting in parasitic outbreaks. Understanding of host defense mechanisms is needed to predict and mitigate against the consequences of parasite invasion. Using the honey bee Apis mellifera and the mite Varroa destructor, as a host–parasite model, we provide a comprehensive study of a mechanism of parasite detection that triggers a behavioral defense associated with social immunity. Six Varroa-parasitization-specific (VPS) compounds are identified that trigger Varroa-sensitive hygiene (VSH, bees’ key defense against Varroa sp.), enable the selective recognition of a parasitized brood and induce responses that mimic intrinsic VSH activity in bee colonies. We also show that individuals engaged in VSH exhibit a unique ability to discriminate VPS compounds from healthy brood signals. These findings enhance our understanding of a critical mechanism of host defense against parasites, and have the potential to apply the integration of pest management in the beekeeping sector.", journal = "Nature Chemical Biology", author = "Mondet, F. and Blanchard, S. and Barthes, N. and Beslay, D. and Bordier, C. and Costagliola, G. and Hervé, M. R. and Lapeyre, B. and Kim, S. H. and Basso, B. and Mercer, A. R. and Conte, Y. L.", pages = "524+", pmid = 33495646, year = 2021, hal_id = "hal-03121517", peer_reviewing = 1, audience = 2, hal_version = "v1" }K Wierucka, N Barthes, B J Pitcher, B Schaal, I Charrier and R G Harcourt. Chemical Profiles of Integumentary and Glandular Substrates in Australian Sea Lion Pups ( Neophoca cinerea ). Chemical Senses 44:205-214, 2019. URL, DOI BibTeX
@article{wierucka_chemical_profiles_of_2019_hal-02195011, title = "Chemical Profiles of Integumentary and Glandular Substrates in Australian Sea Lion Pups ( Neophoca cinerea )", volume = 44, issn = "0379-864X", url = "http://chemse.oxfordjournals.org/", doi = "10.1093/chemse/bjz008", abstract = "Recognition of individuals or classes of individuals plays an important role in the communication systems of many mammals. The ability of otariid (i.e., fur seal and sea lion) females to locate and identify their offspring in colonies after returning from regular foraging trips is essential to successful pup rearing. It has been shown that olfaction is used to confirm the identity of the pup by the mother when they reunite, yet the processes by which this chemical recognition occurs remain unclear. Using gas chromatography-mass spectrometry, we examined chemical profiles of integumentary and glandular secretions/excretions from pre- and post-molt Australian sea lion pups (Neophoca cinerea) and compared fur and swab samples to assess data collection methods. Multivariate statistics were applied to assess differences in chemical composition between body regions and sexes. We found differences among secretions from various body regions, driven by the distinctiveness of the oral odor mixture. The fine-scale trends in pre- and post-molt pups seem to differ due to changes in the behavior of pups and consequent decrease in the transfer of compounds among adjacent body regions in older pups. Volatile compounds from exocrine substrates were not distinct for different sexes. We also show that swab samples provide better data for exploring social olfaction than fur samples for this species. Obtaining fundamental chemical information, in this case chemical profiles of animals, and discerning differences in chemical composition is an important step toward fully exploring the intricacies of mother-offspring olfactory recognition and its underlying processes.", journal = "Chemical Senses", author = "Wierucka, K. and Barthes, N. and Pitcher, B. J. and Schaal, B. and Charrier, I. and Harcourt, R. G.", pages = "205-214", pmid = 30799500, year = 2019, hal_id = "hal-02195011", peer_reviewing = 1, audience = 2, hal_version = "v1" }K Wierucka, N Barthes, R G Harcourt, B Schaal, I Charrier and B J Pitcher. Chemical fingerprints suggest direct familiarisation rather than phenotype matching during olfactory recognition in Australian sea lions (Neophoca cinerea). Journal of Experimental Marine Biology and Ecology 517:49-53, 2019. URL, DOI BibTeX
@article{wierucka_chemical_fingerprints_suggest_2019_hal-02262499, title = "Chemical fingerprints suggest direct familiarisation rather than phenotype matching during olfactory recognition in Australian sea lions (Neophoca cinerea)", volume = 517, issn = "0022-0981", url = "https://www.elsevier.com/locate/jembe", doi = "10.1016/j.jembe.2019.06.001", abstract = "Olfaction is one of the most commonly used senses for communication among animals and is of particular importance to mother-offspring recognition in mammals. The use of smell in offspring recognition has been well studied, however, we often lack information about the underlying mechanistic basis for olfactory recognition. Using gas chromatography–mass spectrometry (GC–MS), we examine chemical profiles of two different colonies of Australian sea lions (Neophoca cinerea) and assess similarity of chemical fingerprints in mother-pup pairs. This analysis allows us to examine whether a chemical base for phenotype matching exists in this species. Our results showed no GC-detectible mother-offspring similarity in the overall chemical fingerprints, suggesting that direct familiarisation is a more likely mechanism used by Australian sea lion mothers for recognition of their young. Our analysis also demonstrates that colony differences are encoded within chemical fingerprints and appear to be highly influenced by environmental compounds. The study improves our understanding of how Australian sea lion females use odours for selective offspring recognition and the potential importance of environmentally acquired chemical compounds in the overall odour bouquet used in mother-pup interactions.", journal = "Journal of Experimental Marine Biology and Ecology", author = "Wierucka, K. and Barthes, N. and Harcourt, R. G. and Schaal, B. and Charrier, I. and Pitcher, B. J.", pages = "49-53", year = 2019, hal_id = "hal-02262499", peer_reviewing = 1, audience = 2, hal_version = "v1" }R Warneys, M Gaucher, P Robert, S Aligon, S Anton, S Aubourg, N Barthes, F Braud, R Cournol, C Gadenne, C Heintz, M -N Brisset and A Degrave. Acibenzolar-S-Methyl Reprograms Apple Transcriptome Toward Resistance to Rosy Apple Aphid. Frontiers in Plant Science 9:1795, 2018. URL, DOI BibTeX
@article{warneys_acibenzolarsmethyl_reprograms_apple_2018_hal-02102171, title = "Acibenzolar-S-Methyl Reprograms Apple Transcriptome Toward Resistance to Rosy Apple Aphid", volume = 9, issn = "1664-462X", url = "https://www.frontiersin.org/articles/10.3389/fpls.2018.01795/full", doi = "10.3389/fpls.2018.01795", abstract = "Acibenzolar-S-methyl (ASM) is a chemical compound, which is able to induce resistance in several model and non-model plants, but the end-players of this induced defense remain ill-defined. Here, we test the hypothesis that treatment with ASM can protect apple (Malus × domestica) against the rosy apple aphid (Dysaphis plantaginea) and investigate the defense molecules potentially involved in resistance. We measured aphid life traits and performed behavioral assays to study the effect of ASM on plant resistance against the aphid, and then combined transcriptomic, bioinformatics, metabolic and biochemical analyses to identify the plant compounds involved in resistance. Plants treated with ASM negatively affected several life traits of the aphid and modified its feeding and host seeking behaviors. ASM treatment elicited up-regulation of terpene synthase genes in apple and led to the emission of (E,E)-α-farnesene, a sesquiterpene that was repellent to the aphid. Several genes encoding amaranthin-like lectins were also strongly up-regulated upon treatment and the corresponding proteins accumulated in leaves, petioles and stems. Our results link the production of specific apple proteins and metabolites to the antibiosis and antixenosis effects observed against Dysaphis plantaginea, providing insight into the mechanisms underlying ASM-induced herbivore resistance.", journal = "Frontiers in Plant Science", author = "Warneys, R. and Gaucher, M. and Robert, P. and Aligon, S. and Anton, S. and Aubourg, S. and Barthes, N. and Braud, F. and Cournol, R. and Gadenne, C. and Heintz, C. and Brisset, M.-N. and Degrave, A.", pages = 1795, pmid = 30619387, year = 2018, hal_id = "hal-02102171", peer_reviewing = 1, audience = 2, hal_version = "v1" }N Barthes and C Grison. First general methods toward aldehyde enolphosphates. Bioorganic Chemistry 40:48-56, 2012. DOI BibTeX
@article{barthes_first_general_methods_2012_hal-03007957, title = "First general methods toward aldehyde enolphosphates", volume = 40, issn = "0045-2068", doi = "10.1016/j.bioorg.2011.11.006", journal = "Bioorganic Chemistry", author = "Barthes, N. and Grison, C.", pages = "48-56", year = 2012, hal_id = "hal-03007957", peer_reviewing = 1, audience = 2, hal_version = "v1" }M Charpentier, M Fontaine, E Cherel, J Renoult, T Jenkins, L Benoit, N Barthès, S Alberts and J Tung. Genetic structure in a dynamic baboon hybrid zone corroborates behavioural observations in a hybrid population. Molecular Ecology 21:715-731, 2012. DOI BibTeX
@article{charpentier_genetic_structure_in_2012_hal-02079621, title = "Genetic structure in a dynamic baboon hybrid zone corroborates behavioural observations in a hybrid population", volume = 21, issn = "0962-1083", doi = "10.1111/j.1365-294X.2011.05302.x", journal = "Molecular Ecology", author = "Charpentier, M. and Fontaine, M. and Cherel, E. and Renoult, J. and Jenkins, T. and Benoit, L. and Barthès, N. and Alberts, S. and Tung, J.", pages = "715-731", year = 2012, hal_id = "hal-02079621", peer_reviewing = 1, audience = 2, hal_version = "v1" }M Charpentier, N Barthes, M Proffit, M Bessière, C Grison and C Fox. Critical thinking in the chemical ecology of mammalian communication: roadmap for future studies. Functional Ecology 26:769-774, 2012. URL, DOI BibTeX
@article{charpentier_critical_thinking_in_2012_hal-02079627, title = "Critical thinking in the chemical ecology of mammalian communication: roadmap for future studies", volume = 26, issn = "0269-8463", url = "https://besjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2435.2012.01998.x", doi = "10.1111/j.1365-2435.2012.01998.x", abstract = "1. Sophisticated and sensitive technologies now allow separation, quantification and chemical characterization of numerous compounds that play roles in chemical communication, chemical defence and aggression, in interactions between conspecific or heterospecific individuals. In the particular subfield of mammalian chemical communication, these rapid technological advances, combined with a frequent lack of technical background, have led to important errors in both chemical characterization of molecules and interpretation of their roles as chemical mediators of communication. 2. The aim of this article is to highlight some of these methodological and analytical pitfalls and to provide a basis for better understanding of chemical mediation of communication in mammals. We compiled the recent literature treating molecules found in mammalian secretions and having putative roles in communication. A selection of 41 published studies dealing with 33 mammal species revealed reports of 857 different molecules. Based on the five main metabolic pathways responsible for the biosynthesis of most known secondary metabolites, we propose nine general biochemical rules that will help researchers to avoid errors of chemical characterization and to aid in interpreting the possible functional role of identified molecules as chemical mediators of mammal communication. 3. Following these nine rules, we show that published studies include reports of molecules that are incorrectly or ambiguously named, molecules of exclusively non-natural origin, molecules produced by other organisms but not directly by mammals, and molecules of biological origin and possibly produced by mammals. Only the last two of these classes could conceivably play roles as mediators of mammalian communication. We discuss the potential roles of these compounds as reported in the publications we reviewed. 4. Our recommendations concerning technical, analytical and statistical aspects of the identification of compounds and interpretation of their roles should help chemical ecologists ask the appropriate questions about the accuracy of their identifications of molecules, the biological relevance of molecules they do identify and the possible functional roles of these molecules in mammalian communication.", journal = "Functional Ecology", author = "Charpentier, M. and Barthes, N. and Proffit, M. and Bessière, M. and Grison, C. and Fox, C.", pages = "769-774", year = 2012, hal_id = "hal-02079627", peer_reviewing = 1, audience = 2, hal_version = "v1" }R Delle-Vedove, N Juillet, J -M Bessiere, C Grison, N Barthes, T Pailler, L Dormont and B Schatz. Colour-scent associations in a tropical orchid: Three colours but two odours. Phytochemistry 72:735-742, 2011. DOI BibTeX
@article{delle-vedove_colourscent_associations_in_2011_hal-01199349, title = "Colour-scent associations in a tropical orchid: Three colours but two odours", volume = 72, issn = "0031-9422", doi = "10.1016/j.phytochem.2011.02.005", abstract = "Colour and scent are the major pollinator attractants to flowers, and their production may be linked by shared biosynthetic pathways. Species with polymorphic floral traits are particularly relevant to study the joint evolution of floral traits. We used in this study the tropical orchid Calanthe sylvatica from Réunion Island. Three distinct colour varieties are observed, presenting lilac, white or purple flowers, and named respectively C. sylvaticavar.lilacina (hereafter referred as var. lilacina), C. sylvaticavar. alba (var. alba) and C. sylvatica var. purpurea (var. purpurea). We investigated the composition of the floral scent produced by these colour varieties using the non-invasive SPME technique in the wild. Scent emissions are dominated by aromatic compounds. Nevertheless, the presence of the terpenoid (E)-4,8-dimethylnona-1,3,7-triène (DMNT) is diagnostic of var. purpurea, with the volatile organic compounds (VOC) produced by some individuals containing up to 60% of DMNT. We evidence specific colour-scent associations in C. sylvatica, with two distinct scent profiles in the three colour varieties: the lilacina-like profile containing no or very little DMNT (\textless2%) and the purpurea-like profile containing DMNT (\textgreater2%). Calanthe sylvatica var. alba individuals group with one or the other scent profile independently of their population of origin. We suggest that white-flowered individuals have evolved at least twice, once from var. lilacina and at least once from var. purpurea after the colonisation of la Réunion. White-flowered individuals may have been favoured by the particular pollinator fauna characterising the island. These flowering varieties of C. sylvatica, which display three colours but two scents profiles prove that colour is not always a good indicator of odour and that colour-scent associations may be complex, depending on pollination ecology of the populations concerned.", journal = "Phytochemistry", author = "Delle-Vedove, R. and Juillet, N. and Bessiere, J.-M. and Grison, C. and Barthes, N. and Pailler, T. and Dormont, L. and Schatz, B.", pages = "735-742", year = 2011, hal_id = "hal-01199349", peer_reviewing = 1, audience = 2, hal_version = "v1" }C Grison, N Barthes, C Finance and R E Duval. Synthesis and antibacterial activity of novel enolphosphate derivatives. Bioorganic Chemistry 38:218 - 223, 2010. DOI BibTeX
@article{grison_synthesis_and_antibacterial_2010_hal-01650292, title = "Synthesis and antibacterial activity of novel enolphosphate derivatives", volume = 38, issn = "0045-2068", doi = "10.1016/j.bioorg.2010.06.006", journal = "Bioorganic Chemistry", author = "Grison, C. and Barthes, N. and Finance, C. and Duval, R. E.", pages = "218 - 223", year = 2010, hal_id = "hal-01650292", peer_reviewing = 1, audience = 2, hal_version = "v1" }C Grison, H Chibli, N Barthes and P Coutrot. One-Pot Carbanionic Synthesis of P 1 , P 2 -Diglycosyl, P 1 , P 1 , P 2 -Triglycosyl, and P 1 , P 1 , P 2 , P 2 -Tetraribosyl Methylenediphosphonates. Journal of Organic Chemistry 71:7978-7988, 2006. DOI BibTeX
@article{grison_onepot_carbanionic_synthesis_2006_hal-03007998, title = "One-Pot Carbanionic Synthesis of P 1 , P 2 -Diglycosyl, P 1 , P 1 , P 2 -Triglycosyl, and P 1 , P 1 , P 2 , P 2 -Tetraribosyl Methylenediphosphonates", volume = 71, issn = "0022-3263", doi = "10.1021/jo061087v", journal = "Journal of Organic Chemistry", author = "Grison, C. and Chibli, H. and Barthes, N. and Coutrot, P.", pages = "7978-7988", year = 2006, hal_id = "hal-03007998", peer_reviewing = 1, audience = 2, hal_version = "v1" }M Calmès, R Akkari, N Barthes, F Escale and J Martinez. Asymmetric Baylis–Hillman reactions using (R)-4-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl) benzoic acid acrylate derivatives in solution and on solid support. Tetrahedron: Asymmetry 16:2179-2185, 2005. DOI BibTeX
@article{calmès_asymmetric_baylis–hillman_reactions_2005_hal-03007971, title = "Asymmetric Baylis–Hillman reactions using (R)-4-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl) benzoic acid acrylate derivatives in solution and on solid support", volume = 16, issn = "0957-4166", doi = "10.1016/j.tetasy.2005.05.016", journal = "Tetrahedron: Asymmetry", author = "Calmès, M. and Akkari, R. and Barthes, N. and Escale, F. and Martinez, J.", pages = "2179-2185", year = 2005, hal_id = "hal-03007971", peer_reviewing = 1, audience = 2, hal_version = "v1" }A Leconte, P Lucas, N Barthes, B Buatois, J Huguenin, E Coutagne, H Duval and M Staudt. COV de l'amandier : discrimination des émissions au printemps pour la mise au point d'un mélange attractif du ravageur Eurytoma amygdali. In GDR MediatEC annual meeting. 2022. BibTeX
@inproceedings{leconte_cov_de_lamandier_2022_hal-03896122, title = "COV de l'amandier : discrimination des émissions au printemps pour la mise au point d'un mélange attractif du ravageur Eurytoma amygdali", booktitle = "GDR MediatEC annual meeting", author = "Leconte, A. and Lucas, P. and Barthes, N. and Buatois, B. and Huguenin, J. and Coutagne, E. and Duval, H. and Staudt, M.", year = 2022, hal_id = "hal-03896122", peer_reviewing = 1, audience = 2, proceedings = 0, invited_communication = 0, hal_version = "v1" }A Leconte, B Buatois, N Barthes, E Coutagne, H Duval, M Staudt and P Lucas. Identification des COV actifs chez les femelles Eurytoma amygdali. In 7ème rencontre annuelle du GDR O3. 2022. BibTeX
@inproceedings{leconte_identification_des_cov_2022_hal-04143630, title = "Identification des COV actifs chez les femelles Eurytoma amygdali", booktitle = "7ème rencontre annuelle du GDR O3", author = "Leconte, A. and Buatois, B. and Barthes, N. and Coutagne, E. and Duval, H. and Staudt, M. and Lucas, P.", year = 2022, hal_id = "hal-04143630", peer_reviewing = 1, audience = 2, proceedings = 0, invited_communication = 0, hal_version = "v1" }N Barthes. MZmine 3 -GC-MS. 2024. BibTeX
@book{barthes_mzmine_3_gcms_2024_hal-04434774, title = "MZmine 3 -GC-MS", abstract = "This document contains the basics to compute the data obtained by gas chromatography coupled to mass spectrometry. We will learn how to convert the manufacturer files to open format files, create a reproducible pipeline to batch clean, integrate and align your chromatograms. At last, I'll give you some tips to annotate the molecules. I won't consider ESI, HRMS, MS2 spectra nor statistical analysis on the obtained data but MZmine can do it too!", author = "Barthes, N.", pages = 12, year = 2024, hal_id = "hal-04434774", audience = 2, hal_version = "v1" }N Barthes and O Thomas. PETIT GUIDE DE CHIMIE POUR L'ÉCOLOGIE CHIMIQUE : Tome 2 - Les bases de chimie pour appréhender les grandes voies métaboliques. 2020. BibTeX
@book{barthes_petit_guide_de_2020_hal-04485021, title = "PETIT GUIDE DE CHIMIE POUR L'ÉCOLOGIE CHIMIQUE : Tome 2 - Les bases de chimie pour appréhender les grandes voies métaboliques", abstract = "Vous trouverez dans ce second document un aperçu des grandes voies métaboliques conduisant aux métabolites spécialisés.", author = "Barthes, N. and Thomas, O.", year = 2020, hal_id = "hal-04485021", audience = 3, hal_version = "v1" }N Barthes and O Thomas. Petit guide de chimie pour l'écologie chimique : Tome 1 - Les bases de chimie pour appréhender Nomenclature et Stéréochimie. 2020. BibTeX
@book{barthes_petit_guide_de_2020_hal-04485014, title = "Petit guide de chimie pour l'écologie chimique : Tome 1 - Les bases de chimie pour appréhender Nomenclature et Stéréochimie", abstract = "Vous trouverez donc dans ce premier document (i) les bases de nomenclature en chimie organique et (ii) quelques notions de stéréochimie qui vous permettront de comprendre le second document qui présentera un aperçu des grandes voies métaboliques conduisant aux métabolites spécialisés.", author = "Barthes, N. and Thomas, O.", year = 2020, hal_id = "hal-04485014", audience = 3, hal_version = "v1" }N Barthes, J C Caissard, J Just and X Fernandez. Outils chimiques, bio-informatiques et bases de données en écologie chimique. In Écologie chimique. 2017. URL BibTeX
@incollection{barthes_outils_chimiques_bioinformatiques_2017_hal-03228447, title = "Outils chimiques, bio-informatiques et bases de données en écologie chimique", booktitle = "Écologie chimique", url = "https://www.istegroup.com/fr/produit/ecologie-chimique/", abstract = "Ce chapitre présente quelques techniques utilisées en Écologie chimique. Depuis quelques années, des équipements de plus en plus performants permettent en effet d’obtenir des analyses profondes de métabolites secondaires et d’acides nucléiques. Ces approches vont souvent de pair avec la production de masses de données énormes rendant indispensable la comparaison automatique avec des bases de données en ligne. Des innovations techniques majeures, basées sur ces performances d’analyse chimique, ont aussi vu le jour en imagerie. Il est ainsi de plus en plus fréquent d’imager une molécule donnée avec une résolution approchant l’ordre du µm. Ce chapitre présente ces aspects ainsi que quelques axes possibles d’innovation.", author = "Barthes, N. and Caissard, J. C. and Just, J. and Fernandez, X.", year = 2017, hal_id = "hal-03228447", audience = 2, hal_version = "v1" }
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