Génétique et Ecologie Evolutive

Patrik NOSIL

ERC Principal Investigator

P Nosil


Campus du CNRS
1919, route de Mende
34293 Montpellier 5

Tél : +33/0 4 67 61 xx xx
Fax : +33/0 4 67 61 33 36



1999.          B.Sc. Biology. University of Victoria, Canada.

2001-2006. Ph.D. Biology. Simon Fraser University, Canada (advisor Dr. Bernard Crespi).


Research in our group focuses on three main themes: (1) the evolutionary processes driving and constraining the formation of new species, (2) the ecological effects of rapid evolution (‘eco-evolutionary dynamics’), and (3) the genetics of adaptation. Various approaches are used to address these topics, including field observations, manipulative field and lab experiments, theoretical modeling, and next-generation DNA sequence data. Our main study system are Timema stick insects.


Adaptation, Ecology, Evolution, Genomics, Speciation

Representative Publications

Villoutreix, R., C.F. de Carvalho, V. Soria-Carrasco, D. Lindtke, M. De-la-Mora, M. Muschick, J.L. Feder, T.L. Parchman, Z. Gompert, and P. Nosil. 2020. Large-scale mutation in the evolution of a gene complex for cryptic coloration. Science 369: 460-466.

Nosil, P., R. Villoutreix, C.F. de Carvalho, J.L. Feder, T.L. Parchman, and Z. Gompert. 2020. Ecology shapes epistasis in a genotype-phenotype-fitness map for stick insect colour. Nature Ecology and Evolution https://doi.org/10.1038/s41559-020-01305-y.

Dunning, L.T., J.J. Moreno-Villena, J.K. Olofsson, Y. Yang, C. Parisod, J. Dionora, R. R. Choudhury, W.P. Quick, M. Park, J.L. Bennetzen, G. Besnard, P. Nosil, C.P. Osborne, and P-A. Christin. 2019. Lateral transfers of large DNA fragments spread functional genes among grasses. Proceedings of the National Academy of Sciences USA 116: 4416-4425.

Nosil, P., R. Villoutreix, C.F. de Carvalho, T.E. Farkas, V. Soria-Carrasco, J.L. Feder, B.J. Crespi, and Z. Gompert. 2018. Natural selection and the predictability of evolution in Timema stick insects. Science 359: 765-770.

Rüdiger R., M. Muschick, D. Lindtke, R. Villoutreix, A.A. Comeault, T.E. Farkas, K. Lucek, E. Hellen, V. Soria-Carrasco, S.R. Dennis, C.F. de Carvalho, R.J. Safran, C.P. Sandoval, J.L. Feder, R. Gries, B.J. Crespi, G. Gries, Z. Gompert, and P. Nosil. 2017. Transitions between phases of genomic differentiation during stick-insect speciation. Nature Ecology and Evolution 1: 0082.

Soria-Carrasco, V., Z. Gompert, A.A. Comeault, T.E. Farkas, T.L. Parchman, J.S. Johnson, C.A. Buerkle, J.L. Feder, J. Bast, T. Schwander, S.P. Egan, B.J. Crespi, and P. Nosil. 2014. Stick insect genomes reveal natural selection’s role in parallel speciation. Science 344: 738-742.

Flaxman, S.M., A. Wacholder, J.L. Feder, and P. Nosil. 2014. Theoretical models of the influence of genomic architecture on the dynamics of speciation. Molecular Ecology 23: 4074-4088

Farkas, T.E., T. Mononen, A.A. Comeault, I. Hanksi, and P. Nosil. 2013. Evolution of camouflage drives rapid ecological change within an insect community. Current Biology 23: 1835-1843.

Michel, A.P., S. Sim, T. Powell, P. Nosil, and J.L. Feder. 2010. Widespread genomic divergence during sympatric speciation. Proceedings of the National Academy of Sciences USA 107: 9724-9729.

Funk, D.J., P. Nosil, and B. Etges. 2006. Ecological divergence exhibits consistently positive associations with reproductive isolation across disparate taxa. Proceedings of the National Academy of Sciences USA 103: 3209-3213.

Nosil, P., and B.J. Crespi. 2006. Experimental evidence that predation promotes divergence during adaptive radiation. Proceedings of the National Academy of Sciences USA 103: 9090-9095. 

Nosil, P., B.J. Crespi, and C.P. Sandoval. 2002. Host-plant adaptation drives the parallel evolution of reproductive isolation. Nature 417: 440-443.