- Publication : 13 mai 2020
29 janvier 2021, 11h30 (diffusion en visioconférence).
What determines the diversity of pathogenic microbial communities in nature?
Link to seminar will be posted here
Department of Evolutionary Biology and Environmental Studies, University of Zurich, Switzerland
Pathogens are prevalent across all ecosystems and they may have strong negative effects on their hosts. Hence, there is a pressing need to understand determinants of risks of infection and how these evolve. To date, host-pathogen interactions have been largely viewed within the ‘one host-one parasite’ framework although in reality the same host may be attacked by a myriad of pathogenic microbes. As molecular tools have become increasingly available for the study of parasites, we now know that a single host individual can support a highly diverse pathogen community. However, remarkably little is known about the factors that determine which pathogens co-occur within the same host individual, how they interact and what this diversity means for disease ecology. In my talk I will present case studies of within host pathogen strain and species diversity, and what we know to date of the determinants of this diversity.
Sallinen, S., Norberg, A., Susi, H. & Laine, A.-L. 2020. Intraspecific host variation plays a key role in virus community assembly. Nature Communications, 11,5610 (2020). doi: 10.1038/s41467-020-19273-z
Halliday. F. W., Penczykowski, R., Barres, B., Eck, J., Numminen, E. & Laine, A.-L. 2020. Facilitative priority effects drive parasite assembly under coinfection. Nature Ecology & Evolution 4: 1510–152. doi: 10.1038/s41559-020-01289-9
Laine, A.-L., Barrès, B., Numminen, E. & Sirén, J. 2019. Variable opportunities for outcrossing result in hotspots of novel genetic variation in a pathogen metapopulation. eLife, 8:e47091. doi:10.7554/eLife.47091