Génétique et Ecologie Evolutive

Christoph HAAG

Chargé de Recherche C Haag2

Evolutionary genetics and genomics.


My main current researchinterests include evolution in spatially structured populations, evolution of ageing, and evolution of reproductive modes. I combine experiments with the analysis of NGS data. My main empirical study systems are the small crustaceans Daphnia and Artemia.



Campus du CNRS
1919, route de Mende
34293 Montpellier 5

Tél : +33/0 4 67 61 32 91
Fax : +33/0 4 67 61 33 36

profile on ResearchGate, GoogleScholar


Brief CV

since 2013:  Permanent Researcher (CR1) CNRS, HDR 2015
2007-2013:  Group Leader, Univ. Fribourg, Switzerland
2005-2007:  Marie Curie Fellow, Univ. Edinburgh, Scotland
2004-2005:  Post-Doc, Univ. Helsinki, Finland
2000-2004:  PhD, Univ. Basel and Fribourg, Switzerland

Research keywords: Evolution of Ageing, Genetic drift, Local adaptation, Breeding systems, Daphnia, Population Genomics, Asexuality, Automixis, Recombination, Meiosis.



Molinier, C., C.M.O. Reisser, P. Fields, A. Ségard, Y. Galimov, and C.R. Haag 2018. Identification of general patterns of sex-biased expression in Daphnia, a genus with environmental sex determination. G3 Genes, Genomes, Genetics, in press. BioRxiv https://doi.org/10.1101/269951

Bekker, E.I., D.P. Karabanov, Y.R. Galimov, C.R. Haag, T.V. Neretina, and A.A. Kotov. 2018. Phylogeography of Daphnia magna Straus (Crustacea: Cladocera) in Northern Eurasia. PLoS One, in press.

Lohr, J.N. and C. R. Haag. 2017. Parasite-driven replacement of a sexual by a closely related asexual taxon in nature. BioRxiv https://doi.org/10.1101/143446

Haag, C.R., L. Theodosiou, R. Zahab, and T. Lenormand. 2017. Low recombination rates in sexual species and sex-asex transitions. Phil. Trans. R. Soc. B., 372: 20160461. PDF

Reisser, C.M.O., D. Fasel, E. Hurlimann, M. Dukic, C. Haag-Liautard, V. Thuillier, Y. Galimov, and C.R. Haag. 2017. Transition from environmental to partial genetic sex determination in Daphnia through the evolution of a female-determining incipient W-chromosome. bioRxiv, 064311, Mol. Biol. Evol., 34: 575-588. PDF Suppl.

Dukic, M., D. Berner, M. Roesti, C.R. Haag*, and D. Ebert*. 2016. A high-density genetic map reveals variation in recombination rate across the genome of Daphnia magna. BMC Genetics, 17: 137. PDF

Lenormand, T., J. Engelstädter, S. E. Johnston, E. Wijnker, and C.R. Haag. 2016. Evolutionary mysteries in meiosis. bioRxiv, 050831, Phil. Trans. R. Soc. B., 371: 20160001. PDF

Orsini, L., D. Gilbert, R. Podicheti, M. Jansen, J. B. Brown, O. Shams Solari, K. I. Spanier, J. K. Colbourne, D. Rush, E. Decaestecker, J. Asselman, K. A.C. De Schamphelaere, D. Ebert, C. R. Haag, J. Kvist, C. Laforsch, A. Petrusek, A. P. Beckerman, T. J. Little, A. Chaturvedi, M. E. Pfrender, L. De Meester, and M. J. Frilander. 2016. Daphnia magna transcriptome by RNA-Seq across 12 environmental stressors. Scientific data 3. PDF

Lohr, J.N. and C.R. Haag. 2015. Genetic load, inbreeding depression and hybrid vigour covary with population size: an empirical evaluation of theoretical predictions. Evolution, 69: 3109–3122. PDF

Nougué, O., N. Rode, R. Zahab, A. Ségard, L.-M. Chevin, C.R. Haag, and T. Lenormand. 2015. Automixis in Artemia: solving a century-old controversy. J. Evol. Biol., 28: 2337–2348. PDF

Svendsen, N., C. M. O. Reisser, M. Dukic, V. Thuillier, A. Segard, C. Haag-Liautard, D. Fasel, E. Hürlimann, T. Lenormand, Y. Galimov, and C.R. Haag. Uncovering cryptic asexuality in Daphnia magna by RAD-sequencing. Genetics, 201:1143-1155. PDF

Roulin, A.C., M. Mariadassou, M. D. Hall, J.-C. Walser, C.R. Haag, and D. Ebert. 2015 High genetic variation in resting-stage production in a metapopulation: Is there evidence for local adaptation? Evolution, 69: 2747–2756. PDF

Fields, P., C.M.O. Reisser, M. Dukic, C.R. Haag, and D. Ebert.2015 Genes mirror geography in Daphnia magna. Mol. Ecol. 24: 4521–4536. PDF

Nepoux, V., A. Babin, C. Haag, T. J. Kawecki, and A. Le Rouzic. 2015. Quantitative genetics of learning ability and resistance to stress in Drosophila melanogaster. Ecology and Evolution 5: 543-556. PDF

Lohr, J.N., P. David, and C.R. Haag. 2014. Reduced lifespan and increased ageing driven by genetic drift in small populations. Evolution 68: 2494–2508. PDF Suppl. Suppl.

Roulin, A.C., J. Routtu, M.D. Hall, T. Janicke, I. Colson, C.R. Haag and D. Ebert. 2013. Local adaptation of sex-induction in a facultative sexual crustacean: insights from QTL mapping and natural population of Daphnia magna. Mol. Ecol. 22: 3567-3579. PDF

Robinson, J.D., C.R. Haag, D.W. Hall, V.I. Pajunen, and J.P. Wares. 2012. Genetic estimates of population age in the water flea, Daphnia magna. J. Hered. 103: 887–897. PDF

Frey, D.J., C.R. Haag, G. Kozlowski, and P. Mráz. 2012. High genetic and morphological diversity despite range contraction in the diploid Hieracium eriophorum (Asteraceae) endemic to the coastal sand dunes of South-Western France. Bot. J. Linn. Soc. 169: 365–377. PDF

Walser, B. and C.R. Haag. 2012. Strong intraspecific variation in genetic diversity and genetic differentiation in Daphnia magna : the effects of population turnover and population size. Mol. Ecol. 21: 851–861. PDF

Brites, D., F. Encinas-Viso, D. Ebert, L. Du Pasquier, and C.R. Haag. 2011. Population genetics of duplicated alternatively spliced exons of the dscam gene in Daphnia and Drosophila. PLoS One 6: e27947. PDF

Joron, M., N. Chamberlain, L. Frézal, R. Jones, L. Ferguson, C.R. Haag, P. A. Wilkinson, S.W. Baxter, C. Davidson, R. Glithero, C. Lloyd, R. Clark, S. Humphrey, S. Sims, J. Rogers, M. Jones, C. D. Jiggins, R.H. ffrench-Constant. 2011. Chromosomal rearrangements drive the evolution of a wing-pattern supergene in a polymorphic butterfly. Nature 477: 203–206. PDF Suppl.

Galimov, Y., B. Walser, and C.R. Haag. 2011. Frequency and inheritance of non male producing clones in Daphnia magna: Evolution towards sex specialization in a cyclical parthenogen? J. Evol. Biol. 24 1572–1583. PDF Suppl.

Népoux, V., C.R. Haag, and T. Kawecki. 2010. Effects of inbreeding on aversive learning in Drosophila. J. Evol. Biol. 23: 2333–2345. PDF

Lehto, M. and C.R. Haag. 2010. Ecological differentiation between coexisting sexual and asexual strains of Daphnia pulex. J. Anim. Ecol. 79: 1241–1250. PDF

Wheat, C.W., C.R. Haag, J, Marden, I. Hanski, and M. Frilander. 2010. Nucleotide polymorphism at a gene (Pgi) under balancing selection in a butterfly metapopulation. Mol. Biol. Evol. 27: 267–281. PDF

Haag, C.R., S.J. McTaggart, A. Didier, T.J. Little, and D. Charlesworth. 2009. Nucleotide polymorphism and within-gene recombination in Daphnia magna and Daphnia pulex, two cyclical parthenogens. Genetics 182: 313–323. PDF

Orsini, L., C.W. Wheat, C.R. Haag, J. Kvist, M.J. Frilander, and I. Hanski. 2009. Fitness differences associated with Pgi SNP genotypes in the Glanville fritillary butterfly (Melitaea cinxia). J. Evol. Biol. 22: 367–375. PDF

Zbinden, M., C.R. Haag, and D. Ebert. 2008. Experimental evolution of field populations of Daphnia magna in response to parasite treatment. J. Evol. Biol. 21: 1068–1078. PDF

Haag, C.R., and D. Roze. 2007. Genetic load in sexual and asexual diploids: segregation, dominance and genetic drift. Genetics 176: 1663–1678. PDF

Haag, C.R., and D. Ebert. 2007. Genotypic selection in Daphnia populations consisting of inbred sibships J. Evol. Biol. 20: 881–891. PDF

Haag, C.R., M. Riek, J.W. Hottinger, V.I. Pajunen, and D. Ebert. 2006. Founder events as determinants of within-island and among-island genetic structure of Daphnia metapopulations. Heredity 96: 150158. PDF

Haag, C.R., M. Saastamoinen, J.H. Marden, and I. Hanski. 2005. A candidate locus for variation in dispersal rate in a butterfly metapopulation. Proc. R. Soc. Lond. B 272: 2449–2456. PDF

Haag, C.R., M. Riek, J.W. Hottinger, V.I. Pajunen, and D. Ebert. 2005. Genetic diversity and genetic differentiation in Daphnia metapopulations with subpopulations of known age. Genetics 170: 18091820. PDF

Haag, C.R. and D. Ebert. 2004. Parasite-mediated selection in experimental metapopulations of Daphnia magna. Proc. R. Soc. Lond. B 271: 21492155. PDF

Haag, C.R. and D. Ebert. 2004. A new hypothesis to explain geographic parthenogenesis. Ann. Zool. Fennici 41:539544. PDF

Haag, C.R., O. Sakwinska, and D. Ebert. 2003. Test of synergistic interaction between infection and inbreeding in Daphnia magna. Evolution 57:777783. PDF

Haag, C.R., J. Hottinger, M. Riek, and D. Ebert. 2002. Strong inbreeding depression in a Daphnia metapopulation. Evolution 56:518526. PDF

Ebert, D., C. Haag, J. Hottinger, M. Riek, and V.I. Pajunen. 2002. A selective advantage to immigrant genes in a Daphnia metapopulation. Science 295:485488. PDF