Génétique et Ecologie Evolutive

Christoph HAAG

Chargé de Recherche C Haag2

Evolutionary genetics and genomics.


My main current researchinterests include evolution in spatially structured populations, evolution of ageing, and evolution of reproductive modes. I combine experiments with the analysis of NGS data. My main empirical study systems are the small crustaceans Daphnia and Artemia.



Campus du CNRS
1919, route de Mende
34293 Montpellier 5

Tél : +33/0 4 67 61 32 91
Fax : +33/0 4 67 61 33 36

profile on ResearchGate, GoogleScholar


Brief CV

since 2013:  Permanent Researcher (CR1) CNRS, HDR 2015
2007-2013:  Group Leader, Univ. Fribourg, Switzerland
2005-2007:  Marie Curie Fellow, Univ. Edinburgh, Scotland
2004-2005:  Post-Doc, Univ. Helsinki, Finland
2000-2004:  PhD, Univ. Basel and Fribourg, Switzerland

Research keywords: Evolution of Ageing, Genetic drift, Local adaptation, Breeding systems, Daphnia, Population Genomics, Asexuality, Automixis, Recombination, Meiosis.



Reisser, C. M. O., D. Fasel, E. Hurlimann, M. Dukic, C. Haag-Liautard, V. Thuillier, Y. Galimov, and C. R. Haag. 2017. Transition from environmental to partial genetic sex determination in Daphnia through the evolution of a female-determining incipient W-chromosome. bioRxiv 064311, Mol. Biol. Evol. in press.

Dukic, M., D. Berner, M. Roesti, C. R. Haag*, and D. Ebert*. 2016. A high-density genetic map reveals variation in recombination rate across the genome of Daphnia magna. BMC Genetics, 17: 137.

Lenormand, T., J. Engelstädter, S. E. Johnston, E. Wijnker, and C. R. Haag. 2016. Evolutionary mysteries in meiosis. bioRxiv, 050831, Phil. Trans. R. Soc. B., 371: 20160001.

Orsini, L., D. Gilbert, R. Podicheti, M. Jansen, J. B. Brown, O. Shams Solari, K. I. Spanier, J. K. Colbourne, D. Rush, E. Decaestecker, J. Asselman, K. A.C. De Schamphelaere, D. Ebert, C. R. Haag, J. Kvist, C. Laforsch, A. Petrusek, A. P. Beckerman, T. J. Little, A. Chaturvedi, M. E. Pfrender, L. De Meester, and M. J. Frilander. 2016. Daphnia magna transcriptome by RNA-Seq across 12 environmental stressors. Scientific data 3.

Lohr, J. N. and C. R. Haag. 2015. Genetic load, inbreeding depression and hybrid vigour covary with population size: an empirical evaluation of theoretical predictions. Evolution, 69: 3109–3122..

Nougué, O., N. Rode, R. Zahab, A. Ségard, L.-M. Chevin, C. R. Haag, and T. Lenormand. 2015. Automixis in Artemia: solving a century-old controversy. J. Evol. Biol., 28: 2337–2348.

Svendsen, N., C. M. O. Reisser, M. Dukic, V. Thuillier, A. Segard, C. Haag-Liautard, D. Fasel, E. Hürlimann, T. Lenormand, Y. Galimov, and C. R. Haag. Uncovering cryptic asexuality in Daphnia magna by RAD-sequencing. Genetics, 201:1143-1155.

Roulin, A. C., M. Mariadassou, M. D. Hall, J.-C. Walser, C. R. Haag, and D. Ebert. 2015 High genetic variation in resting-stage production in a metapopulation: Is there evidence for local adaptation? Evolution, 69: 2747–2756.

Fields, P., C. M. O. Reisser, M. Dukic, C. R. Haag, and D. Ebert.2015 Genes mirror geography in Daphnia magna. Mol. Ecol. 24: 4521–4536.

Nepoux, V., A. Babin, C. Haag, T. J. Kawecki T.J., and A. Le Rouzic. 2015. Quantitative genetics of learning ability and resistance to stress in Drosophila melanogaster. Ecology and Evolution 5: 543-556.

Lohr, J. N.. P. David, and C. R. Haag. 2014. Reduced lifespan and increased ageing driven by genetic drift in small populations. Evolution 68: 2494–2508.

Roulin, A. C., J. Routtu, M. D. Hall, T. Janicke, I. Colson, C. R. Haag and D. Ebert. 2013. Local adaptation of sex-induction in a facultative sexual crustacean: insights from QTL mapping and natural population of Daphnia magna. Mol. Ecol. 22: 3567-3579.

Robinson, J. D., C. R. Haag, D. W. Hall, V. I. Pajunen, and J. P. Wares. 2012. Genetic estimates of population age in the water flea, Daphnia magna. J. Hered. 103: 887–897.

Frey, D. J., C. R. Haag, G. Kozlowski, and P. Mráz. 2012. High genetic and morphological diversity despite range contraction in the diploid Hieracium eriophorum (Asteraceae) endemic to the coastal sand dunes of South-Western France. Bot. J. Linn. Soc. 169: 365–377.

Walser, B. and C. R. Haag. 2012. Strong intraspecific variation in genetic diversity and genetic differentiation in Daphnia magna : the effects of population turnover and population size. Mol. Ecol. 21: 851–861.

Brites, D., F. Encinas-Viso, D. Ebert, L. Du Pasquier, and C. R. Haag. 2011. Population genetics of duplicated alternatively spliced exons of the dscam gene in Daphnia and Drosophila. PLoS One 6: e27947.

Joron, M., N. Chamberlain, L. Frézal, R. Jones, L. Ferguson, C. R. Haag, P. A. Wilkinson, S. W. Baxter, C. Davidson, R. Glithero, C. Lloyd, R. Clark, S. Humphrey, S. Sims, J. Rogers, M. Jones, C. D. Jiggins, R. H. ffrench-Constant. 2011. Chromosomal rearrangements drive the evolution of a wing-pattern supergene in a polymorphic butterfly. Nature 477: 203–206.

Galimov, Y., B. Walser, and C. R. Haag. 2011. Frequency and inheritance of non male producing clones in Daphnia magna: Evolution towards sex specialization in a cyclical parthenogen? J. Evol. Biol. 24 1572–1583.

Népoux, V., C. R. Haag, and T. Kawecki. 2010. Effects of inbreeding on aversive learning in Drosophila. J. Evol. Biol. 23: 2333–2345.

Lehto, M. and C. R. Haag. 2010. Ecological differentiation between coexisting sexual and asexual strains of Daphnia pulex. J. Anim. Ecol. 79: 1241–1250.

Wheat, C. W., C. R. Haag, J, Marden, I. Hanski, and M. Frilander. 2010. Nucleotide polymorphism at a gene (Pgi) under balancing selection in a butterfly metapopulation. Mol. Biol. Evol. 27: 267–281.

Haag, C. R., S. J. McTaggart, A. Didier, T. J. Little, and D. Charlesworth. 2009. Nucleotide polymorphism and within-gene recombination in Daphnia magna and Daphnia pulex, two cyclical parthenogens. Genetics 182: 313–323.

Orsini, L. C. W. Wheat, C. R. Haag, J. Kvist, M. J. Frilander, and I. Hanski. 2009. Fitness differences associated with Pgi SNP genotypes in the Glanville fritillary butterfly (Melitaea cinxia). J. Evol. Biol. 22: 367–375.

Zbinden, M., C. R. Haag, and D. Ebert. 2008. Experimental evolution of field populations of Daphnia magna in response to parasite treatment. J. Evol. Biol. 21: 1068–1078.

Haag, C. R., and D. Roze. 2007. Genetic load in sexual and asexual diploids: segregation, dominance and genetic drift. Genetics 176: 1663–1678.

Haag, C. R., and D. Ebert. 2007. Genotypic selection in Daphnia populations consisting of inbred sibships J. Evol. Biol. 20: 881–891.

Haag, C. R., M. Riek, J. W. Hottinger, V. I. Pajunen, and D. Ebert. 2006. Founder events as determinants of within-island and among-island genetic structure of Daphnia metapopulations. Heredity 96: 150158.

Haag, C. R., M. Saastamoinen, J. H. Marden, and I. Hanski. 2005. A candidate locus for variation in dispersal rate in a butterfly metapopulation. Proc. R. Soc. Lond. B 272: 2449–2456.

Haag, C. R., M. Riek, J. W. Hottinger, V. I. Pajunen, and D. Ebert. 2005. Genetic diversity and genetic differentiation in Daphnia metapopulations with subpopulations of known age. Genetics 170: 18091820.

Haag, C. R. and D. Ebert. 2004. Parasite-mediated selection in experimental metapopulations of Daphnia magna. Proc. R. Soc. Lond. B 271: 21492155.

Haag, C. R. and D. Ebert. 2004. A new hypothesis to explain geographic parthenogenesis. Ann. Zool. Fennici 41:539544.

Haag, C. R., O. Sakwinska, and D. Ebert. 2003. Test of synergistic interaction between infection and inbreeding in Daphnia magna. Evolution 57:777783.

Haag, C. R., J. Hottinger, M. Riek, and D. Ebert. 2002. Strong inbreeding depression in a Daphnia metapopulation. Evolution 56:518526.

Ebert, D., C. Haag, J. Hottinger, M. Riek, and V. I. Pajunen. 2002. A selective advantage to immigrant genes in a Daphnia metapopulation. Science 295:485488.