Accueil

Les gens

Recherche

Publications       

Liens

To English version

Mise à jour
03-déc.-2009

© CEFE -UMR 5175

Thomas Lenormand

tél :         +33 4 67 61 32 15
email:     thomas.lenormand@cefe.cnrs.fr

Thèmes de recherche par mots clés
adaptation, adaptation locale, migration, spéciation, chromosomes, clines, sexe, recombinaison, épistasie, dominance, mutations, résistance, duplications, modifieurs, système de reproduction.

CV bref

DR2 CNRS
HDR (2007)
Thèse en Biologie Evolutive (1998)
Lauréat ERC "starting grant" (2007)
Theodosius Dobzhansky Prize (Society for the Study of Evolution), 2000
Young Investigator Prize (American Society of Naturalists), 2000

Editeur associé 

	2005- 2008
	2004- ...
	2003 - 2007

Enseignement (Master BGAE, spécialité EBE)

Coresponsable du module de Biologie Evolutive Cours: Module de Biologie évolutive et Module de Génétique évolutive

Publications sélectionnées par thèmes

Bourguet, D., T. Lenormand, T. Guillemaud, V. Marcel, D. Fournier, and M. Raymond. 1997. Variation of dominance of newly arisen adaptive genes. Genetics 147:1225-1234.

Labbe, P., A. Berthomieu, C. Berticat, H. Alout, M. Raymond, T. Lenormand, and M. Weill. 2007. Independent duplications of the acetylcholinesterase gene conferring insecticide resistance in the mosquito Culex pipiens. Molecular Biology and Evolution 24:1056-1067. PDF

Labbe, P., C. Berticat, A. Berthomieu,  S. Unal, C. Bernard, M. Weill and T. Lenormand. 2007. Forty years of erratic insecticide resistance evolution in the mosquito Culex pipiens. PLoS Genetics, 3:e205. Synopsis en français PDF

NEW Labbé, P., Sidos, N., Raymond, M., and Lenormand, T., 2009. Resistance Gene Replacement in the Mosquito Culex Pipiens: Fitness Estimation from Long Term Cline Series. Genetics 182:303-312

Lenormand, T., T. Guillemaud, D. Bourguet, and M. Raymond. 1998. Appearance and sweep of a gene duplication: Adaptive response and potential for new functions in the mosquito Culex pipiens. Evolution 52:1705-1712. PDF

NEW Lenormand, T., D. Roze, F. Rousset. 2009. Stochasticity in evolution. Trends in Ecology & Evolution. 24: 157-165. PDF

Martin, G., and T. Lenormand. 2006. A general multivariate extension of Fisher's geometrical model and the distribution of mutation fitness effects across species. Evolution 60:893-907. Awarded Fisher Prize 2007, Best PhD paper published in Evolution in 2006. PDF

Martin, G., and T. Lenormand. 2006. The fitness effect of mutations in stressful environments: a survey in the light of fitness landscape models. Evolution 60:2413-2427. PDF

Martin, G., S.F. Elena and T. Lenormand. 2007. Distributions of epistasis in microbes fit predictions from a fitness landscape model. Nature Genetics 39:555-560. PDF

Billiard, S., and T. Lenormand. 2005. Evolution of migration under kin selection and local adaptation. Evolution 59:13-23. PDF

NEW Debarre F., Lenormand, T. and Gandon S. Evolutionary epidemiology of drug-resistance in space. 2009. PLoS Comp. Biol. 5:e1000337. PDF

NEW Epinat, G., and T. Lenormand. 2009. The evolution of assortative mating and selfing with in- and outbreeding depression. Evolution. 63: 2047-2060. PDF

Guillemaud, T., T. Lenormand, D. Bourguet, C. Chevillon, N. Pasteur, and M. Raymond. 1998. Evolution of resistance in Culex pipiens: Allele replacement and changing environment. Evolution 52:443-453.

Labbe, P., T. Lenormand, and M. Raymond. 2005. On the worldwide spread of an insecticide resistance gene: a role for local selection. Journal of Evolutionary Biology 18:1471-1484. PDF

Lenormand, T. 2002. Gene flow and the limits to natural selection. Trends in Ecology & Evolution 17:183-189. PDF

Lenormand, T., D. Bourguet, T. Guillemaud, and M. Raymond. 1999. Tracking the evolution of insecticide resistance in the mosquito Culex pipiens. Nature 400:861-864. PDF

Lenormand, T., T. Guillemaud, D. Bourguet, and M. Raymond. 1998. Evaluating gene flow using selected markers: A case study. Genetics 149:1383-1392. PDF

Lenormand, T., and M. Raymond. 1998. Resistance management: the stable zone strategy. Proceedings of the Royal Society of London Series B-Biological Sciences 265:1985-1990. PDF

Lenormand, T., and M. Raymond. 2000. Analysis of clines with variable selection and variable migration. American Naturalist 155:70-82. PDF

Lenormand, T. 2003. The evolution of sex dimorphism in recombination. Genetics 163:811-822. PDF

Lenormand, T., and S. P. Otto. 2000. The evolution of recombination in a heterogeneous environment. Genetics 156:423-438. PDF

Lenormand, T., and J. Dutheil. 2005. Recombination difference between sexes: A role for haploid selection. PLoS Biology 3:396-403. PDF

Martin, G., S. P. Otto, and T. Lenormand. 2006. Selection for recombination in structured populations. Genetics 172:593-609. PDF

Otto, S. P., and T. Lenormand. 2002. Resolving the paradox of sex and recombination. Nature Reviews Genetics 3:252-261. PDF

Roze, D., and T. Lenormand. 2005. Self-fertilization and the evolution of recombination. Genetics 170:841-857. PDF

Bierne, N., T. Lenormand, F. Bonhomme, and P. David. 2002. Deleterious mutations in a hybrid zone: can mutational load decrease the barrier to gene flow? Genetical Research 80:197-204. PDF

Fel-Clair, F., J. Catalan, T. Lenormand, and J. Britton-Davidian. 1998. Centromeric incompatibilities in the hybrid zone between house mouse subspecies from Denmark: Evidence from patterns of NOR activity. Evolution 52:592-603.

FelClair, F., T. Lenormand, J. Catalan, J. Grobert, A. Orth, P. Boursot, M. C. Viroux, and J. BrittonDavidian. 1996. Genomic incompatibilities in the hybrid zone between house mice in Denmark: Evidence from steep and non-coincident chromosomal clines for Robertsonian fusions. Genetical Research 67:123-134.

NEW Ganem, G, C. Litel, and T. Lenormand. 2008. Variation in mate preference across a house mouse hybrid zone. Heredity. 6:594-601 PDF

NEW Gay, L., P. Crochet, D. Bell, and T. Lenormand. 2008. Comparing genetic and phenotypic clines in hybrid zones: a window on tension zone models. Evolution 62: 2789-2806 PDF

Lenormand, T., F. FelClair, K. Manolakou, P. Alibert, and J. BrittonDavidian. 1997. Chromosomal transmission bias in laboratory hybrids between wild strains of the two European subspecies of house mice. Genetics 147:1279-1287. PDF

Gimenez O., R. Covas, C. Brown, M. Anderson, M. Bomberger Brown, and T. Lenormand. 2006. Nonparametric estimation of natural selection on a quantitative trait using capture-mark-recapture data. Evolution 60:460-466. PDF

NEW Gimenez O., Gregoire A., Lenormand T. 2009. Estimating and visualizing fitness surfaces using mark-recapture data. Evolution. 63: 3097-3105.

Henry, P. Y., L. Vimond, T. Lenormand, and P. Jarne. 2006. Is delayed selfing adjusted to chemical cues of density in the freshwater snail Physa acuta? Oikos 112:448-455. PDF

NEW Vasileva G.P., Redon S., Amat F., Nikolov P.N., Sanchez M., Lenormand T., Georgiev B.B. Records of cysticercoids of Fimbriarioides tadornae (Maksimova, 1976) and Branchiopodataenia gvozdevi (Maksimova, 1988) (Cyclophyllidea, Hymenolepididae) from brine shrimps at the Mediterranean coasts of Spain and France, with a key to cestodes from Artemia spp. from the Western Mediterranean. Acta Parasitologica 54: 143-150. PDF